Chemical Synaptic Transmission
In order for a nerve impulse to travel from one neuron to another the impulse must travel across the synapse. This is done through the release of a neurotransmitter. There are several steps which occur in order for this to happen.
- AP in the terminal causes voltage gated calcium channels to open.
- Calcium entry triggers exocytosis of synaptic vesicles.
- The transmitter released during exocytosis binds to post synaptic receptors, producing a post synatic response.
The Release of a Neurotransmitter Across a Synapse |
Post Synaptic Receptors
There are two types of post synaptic receptors:
- Ionotropic Receptors: They are ligand gated ion channels which produce faster post synaptic responses. The binding of a neurotransmitter causes them to open and this allows ions to move across the membrane of the post synaptic cell, leading to the formation of a graded potential.
- Metabotropic receptors: The neurotransmitter binds to the receptor which is coupled to a G-protein. The G-protein controls ion channels directly or indirectly through intracellular messengers. This also leads to the formation of a graded potential.
And that's all folks :). If you have any questions please feel free to ask.
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